Does Your Height Increase Your Risk of Varicose Veins?

January 17, 2019

Your height may predict your risk of varicose veins.

A genetic study of nearly half a million people concludes that height is “not just a correlated factor, but an underlying mechanism leading to varicose veins.”


Women are at a higher risk of varicose veins, but new research suggests that height is also a factor.



Varicose veins — also known as spider veins — are “swollen, twisted veins” that can usually be seen right beneath the skin on a person’s legs.



According to the most recent estimates, the condition affects approximately 33 million people in the United States.



The condition is generally considered quite harmless, but previous studies have found a strong association with serious cardiovascular problems, such as blood clotting and deep vein thrombosis .



Also, varicose veins may be moderately painful and aesthetically unpleasant to some people. Now, a large-scale genetic study published in Circulation suggests that a person’s height may determine their risk of developing varicose veins.



The new research was jointly supervised by Dr. Nicholas Leeper, an associate professor of surgery and cardiovascular medicine at Stanford University School of Medicine in California and Dr. Erik Ingelsson, a professor of cardiovascular medicine at Stanford University.



Height may indicate genetic cause



Dr. Leeper and his colleagues applied machine learning and statistical methods to examine the genetic data of 493,519 people who were registered in the UK Biobank database.



Furthermore, the researchers conducted a genome-wide association study in 337,536 of these individuals, 9,577 of whom developed varicose veins.



The study confirmed previously known risk factors for varicose vein disease, such as age, sex, weight, and lifestyle habits including smoking and being sedentary.



However, the study also identified some new risk factors. “We confirmed that having had deep vein thrombosis in the past puts you at increased risk in the future,” Dr. Leeper explains.



Of all the new risk factors identified, the scientists deemed height as the most surprising. “Greater height remained independently associated with varicose veins,” the study authors report.



“We were very surprised to find that height came up from our machine-learning analyses,” says co-first study author Alyssa Flores, a Stanford University medical student.



“Our results strongly suggest height is a cause, not just a correlated factor, but an underlying mechanism leading to varicose veins,” says Dr. Ingelsson.



He adds, “By conducting the largest genetic study ever performed for varicose vein disease, we now have a much better understanding of the biology that is altered in people at risk for the disease.”



“Genes that predict a person’s height may be at the root of this link between height and varicose veins and may provide clues for treating the condition.”  — Dr. Nicholas Leeper



The recent study also identified 30 genes that are not just tied to varicose veins, but also to deep vein thrombosis.



“Varicose vein disease,” says Flores, “is incredibly prevalent but shockingly little is known about the biology.



“We’re hoping,” she adds, “that with this new information, we can create new therapies, as our study highlights several genes that may represent new translational targets.”



As always, we are here at MVI to treat your varicose vein issues. Call 615-849-7490 to schedule a consultation today!

By OBL Marketing May 13, 2026
Benign prostatic hyperplasia, commonly known as an enlarged prostate, is a condition that affects a significant portion of the male population as they age. In fact, research published in the Journal of Clinical Medicine indicates that BPH symptoms affect approximately 80 percent of men by 70 years of age. As the prostate gland grows, it can constrict the urethra, leading to uncomfortable and sometimes debilitating lower urinary tract symptoms. These symptoms can include increased urinary frequency, urgency, a weak stream, and the feeling of incomplete bladder emptying. For many years, the standard approach to treating an enlarged prostate that did not respond to medication was surgery, specifically a procedure known as transurethral resection of the prostate (TURP). While TURP is effective, it is a major surgery that requires general anesthesia, a hospital stay, and a lengthy recovery period. Today, we offer a modern, minimally invasive alternative called Prostate Artery Embolization (PAE). This innovative procedure provides significant relief from BPH symptoms without the need for traditional surgery. Understanding Prostate Artery Embolization Prostate Artery Embolization is a cutting edge, minimally invasive procedure performed by our highly trained interventional radiologists. Instead of cutting away prostate tissue through the urethra, PAE tackles the problem by reducing the blood supply to the prostate gland itself. During the procedure, our interventional radiologist makes a tiny pinhole puncture in the artery of the wrist or groin. Using advanced imaging guidance, a small, flexible tube called a catheter is carefully navigated through the blood vessels until it reaches the specific arteries that supply blood to the prostate. Once the catheter is in the correct position, we inject tiny, round microspheres into these blood vessels. These particles block the blood flow to the prostate tissue. By restricting the blood supply, the prostate gland is essentially starved of the nutrients it needs to maintain its enlarged size. Over the days and weeks following the procedure, the prostate begins to shrink and soften. As the gland decreases in size, the pressure on the urethra is relieved, allowing urine to flow more freely and significantly improving lower urinary tract symptoms. The Benefits of Choosing PAE When considering treatments for an enlarged prostate, it is important to weigh the benefits of each option. PAE offers several distinct advantages over traditional surgical methods, making it an appealing choice for many men. First and foremost, PAE is a minimally invasive outpatient procedure. This means there is no need for a hospital stay. Patients can typically return home the very same day. Furthermore, the procedure does not require general anesthesia, which eliminates the risks and grogginess associated with being put to sleep. Instead, patients receive moderate sedation to keep them comfortable and relaxed throughout the process. Another major benefit of PAE is the significantly reduced risk of sexual side effects. Traditional surgeries like TURP carry a known risk of causing retrograde ejaculation or erectile dysfunction. Because PAE does not involve cutting or removing tissue near the nerves responsible for sexual function, the risk of these side effects is remarkably low. A study in the International Journal of Clinical Practice reported promising results for PAE in preserving antegrade ejaculation and erectile function. This makes PAE an excellent option for men who wish to preserve their sexual health while effectively treating their BPH symptoms. Additionally, the recovery time for PAE is much faster than that of traditional surgery. Most men can resume their normal, light activities within a few days to a week, compared to the several weeks of recovery often required after a TURP procedure. PAE vs TURP: A Treatment Comparison When exploring options for enlarged prostate treatment, it is natural to compare the newer PAE procedure with the long standing gold standard, TURP. Both procedures aim to relieve the symptoms of BPH, but they go about it in very different ways. TURP involves inserting a surgical instrument through the urethra to physically cut away and remove the excess prostate tissue that is blocking urine flow. It is a highly effective procedure with a long track record of success. However, as a more invasive surgery, it requires general or spinal anesthesia and usually involves a hospital stay of one to three days. The recovery period can take anywhere from two to six weeks, during which patients may experience bleeding and discomfort. Furthermore, TURP carries a higher risk of complications, including urinary incontinence and sexual dysfunction. In fact, research shows the reported incidence of retrograde ejaculation after TURP is 50 to 70 percent. In contrast, PAE is performed entirely through the blood vessels, leaving the urethra untouched. There is no cutting, no tissue removal, and no need for a catheter to be left in the penis during recovery. The procedure is performed under conscious sedation, and patients go home the same day. While TURP may offer slightly more immediate relief of symptoms due to the physical removal of tissue, PAE provides a gradual but significant improvement as the prostate shrinks over time. A randomized controlled trial published in The BMJ concluded that PAE is associated with fewer complications than TURP. Furthermore, clinical studies have shown that PAE has a high success rate, with clinical success achieved in 93 percent of patients at 3 months. Ultimately, the choice between PAE and TURP depends on the individual patient's medical history, the size of their prostate, and their personal preferences regarding recovery time and potential side effects. Our team of specialists is dedicated to helping each patient make an informed decision that best suits their unique needs. What to Expect During Recovery Recovery from Prostate Artery Embolization is generally smooth and straightforward. Because it is an outpatient procedure, you will be able to recover in the comfort of your own home. In the days immediately following the procedure, it is common to experience what is known as "post PAE syndrome." This can include mild symptoms such as nausea, a low grade fever, pelvic discomfort, or frequent and sometimes painful urination. These symptoms are a normal part of the healing process and typically resolve on their own within a few days. We will provide you with specific instructions and medications to help manage any discomfort. We advise our patients to take it easy for the first few days after the procedure. You should avoid heavy lifting, strenuous exercise, and any activities that put undue stress on the puncture site in your wrist or groin. Most men find that they can return to work and resume their normal daily routines within a week. As the weeks progress, you will begin to notice a gradual improvement in your urinary symptoms. The prostate will continue to shrink, and the pressure on your urethra will lessen. We will schedule follow up appointments to monitor your progress and ensure that you are achieving the desired results. Is PAE Right for You? If you are experiencing the frustrating symptoms of an enlarged prostate and are looking for a treatment option that avoids the risks and lengthy recovery of traditional surgery, Prostate Artery Embolization may be the ideal solution. It is particularly well suited for men who have very large prostates, those who are not good candidates for surgery due to other health conditions, or those who simply prefer a less invasive approach. At Murfreesboro Vascular and Interventional, our board certified interventional radiologists have extensive experience in performing PAE. We are committed to providing our patients with the highest quality of care using the most advanced, minimally invasive techniques available. To determine if you are a candidate for PAE, we will conduct a comprehensive evaluation, which may include a review of your medical history, a physical exam, and imaging studies such as an ultrasound or MRI of the prostate. We will take the time to discuss your symptoms, answer all of your questions, and help you decide if PAE is the right path forward for you. Do not let an enlarged prostate control your life any longer. Contact us today to schedule a consultation and learn more about how Prostate Artery Embolization in Nashville can help you find relief and get back to enjoying your life.
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